Ingenes Institute is committed to the highest academic and scientific standards in patient care and biomedical research.
The Molecular Diagnostic and Research Laboratory (MDRL) is a scientific investigation department with the main function of establishing detection systems of genomic and transcriptional markers (centered on sophisticated molecular biology techniques).
The resulting findings can contribute to the creation and improvement of couples’ infertility diagnosis and treatment procedures, both in the pre-implantation and in the prenatal phases.
The Molecular Diagnostic and Research Laboratory publications are available at PubMed, the US National Library of Medicine National Institutes of Health.
Lines of investigation
We have defined several lines of investigation that are supported by the combination of state-of-the-art technologies in the areas of genetics and molecular biology. Under the leadership of The Molecular Diagnostic and Research Laboratory, physicians and scientists research the frontiers of reproductive medicine, focusing on improving existing treatments and finding new ways to help patients become parents.
Through an alliance with the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV in Spanish) and the National Council of Science and Technology (abbreviated CONACYT), Ingenes Institute has developed the following lines of research:
Non-invasive gestational diagnosis from the first quarter
This project developed by the Ingenes Molecular Diagnostic and Research Laboratory combines molecular diagnosis procedures with the use of circulating fetal DNA in order to diagnose the main chromosomal abnormalities as early as gestational week 7.
Molecular signatures in the receptive endometrium
In this project, the goal is to develop a trustable and fast test to asses the correct state of a receptive endometrium using molecular markers to allow the physician to transfer a good quality embryo in a uterus with equally good qualification within the same cycle.
With its research team, Ingenes Institute has developed the following services:
Implantation Score: Study of molecular markers in the granulosa cells to improve embryo selection
The granulosa cells accompany the oocyte; they enclose it completely and provide it with physical (protection) and physiological support (nutrition and hormonal).
Modern research throughout the world indicate that the expression of molecular markers in the granulosa cells determines four important elements for the pregnancy:
I) ripening of the oocyte
II) quality of the oocyte
III) potential for fertilization
IV) embryonic development.
At Ingenes, we have designed clear strategies to analyze the molecular markers in the granulosa cells to select for the best oocytes based on parameters of genetic expression that tell us which ones have the greatest potential to achieve pregnancy and our mission with the couple: taking a baby home.
Due to the study of molecular markers in the granulosa cells, Ingenes developed the Implantation Score (IS) services. This Ingenes signature service is a non-invasive genetic study performed on the cells of the egg cell to identify the embryos with the greatest implantation potential to achieve a baby with greater success.
An Ingenes signature service, is a procedure that allows patients to choose the sex of their baby. The selection of the sex of a couple’s baby – also referred to as family balancing. Unlike other centers, this service was developed from the research lines of Ingenes.
With Eligender, the sex of the baby can be determined on the same day of the transfer in 8 hours, with a with a 100% accuracy.