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30 de April, 2025

Ovarian Cancer and Fertility: What Options Do Women Have?

Ovarian cancer is one of the most complex medical challenges faced by women of reproductive age. Although it is primarily associated with general health, its impact on fertility cannot be underestimated. For many women, receiving an ovarian cancer diagnosis not only means facing oncological treatment but also immediately considering how to protect their chances of having children in the future.

In this blog, we will thoroughly explore how ovarian cancer can affect fertility, what options exist to preserve reproductive capacity, and how a specialized approach can radically change the maternity outlook for these women.

What is Ovarian Cancer?

Ovarian cancer originates when abnormal cells in the ovary begin to multiply uncontrollably. It can be of different types, with high-grade serous carcinoma being the most common.

Early detection is difficult because symptoms are often vague or attributed to other causes, and current screening methods are limited. Therefore, many cases are diagnosed at advanced stages.

Some risk factors include:

  • Age over 50 years.
  • Family history of ovarian or breast cancer.
  • Genetic mutations, such as BRCA1 or BRCA2.
  • Endometriosis.
  • Never having had children.

However, ovarian cancer can also affect young women of reproductive age, adding an even more sensitive dimension to the diagnosis: the possibility of compromising their fertility.

How Does Ovarian Cancer Affect Fertility?

The impact on fertility can result from multiple factors:

  • Removal of ovaries or fallopian tubes: Depending on the stage and type of cancer, removal of one or both ovaries and/or fallopian tubes may be required.
  • Chemotherapy and radiotherapy: Some oncological treatments damage the ovaries, reducing or eliminating their reproductive function.
  • Hormonal alteration: Ovarian damage can lead to premature ovarian insufficiency.

Each situation is unique and depends on the stage of cancer, the type of treatment needed, and the patient's maternity wishes.

Fertility Preservation Options Before Treatment

When the diagnosis allows (meaning cancer does not require immediate intervention), there are options to preserve fertility before starting oncological treatment:

1. Egg Freezing

This involves stimulating the ovaries to retrieve multiple eggs, which are then extracted and vitrified for future use.

  • Advantages: Allows the woman to use her own eggs once she has overcome cancer.
  • Ideal for: Young women without a partner or who do not wish to fertilize the eggs at that time.

2. Embryo Freezing

If the woman has a partner or is willing to use a sperm donor, the eggs can be fertilized immediately and the resulting embryos frozen.

  • Advantages: Frozen embryos generally have high survival and long-term viability rates.

3. Ovarian Tissue Preservation

An experimental technique involving the removal and freezing of ovarian tissue before treatment, which can later be reimplanted to restore ovarian function.

  • Advantages: Useful when there is no time for ovarian stimulation.
  • Disadvantages: Not available in all centers and its effectiveness is still under study.

Maternity Options After Treatment

If fertility preservation was not possible before starting treatment or if the ovaries were damaged, there are still alternatives for achieving motherhood:

1. Use of Donated Eggs

Egg donation is a safe and effective option for women who cannot use their own eggs.

  • In vitro fertilization (IVF) is performed using donor eggs and the partner's or a donor's sperm.

2. Surrogacy

When cancer treatment has affected the uterus or there is a risk of recurrence with pregnancy, a surrogate mother can be used.

  • The embryo, created from own or donor eggs, is transferred to the surrogate's uterus.

3. Adoption

Although it is not a direct medical solution, adoption is a legal and loving option for building a family after facing cancer.

Fertility and Cancer Survival: Medical and Emotional Considerations

Overcoming ovarian cancer involves a profound physical and emotional process. That’s why it is important to consider:

  • The safe time to attempt pregnancy: It is generally recommended to wait between 2 and 5 years after treatment.
  • Continuous medical evaluations: To ensure there is no recurrence before attempting pregnancy.
  • Psychological support: To process the cancer experience and the path to motherhood.

Comprehensive support is key so that patients can navigate this journey with confidence and hope.

The Role of a Specialized Fertility Center

Having a team of assisted reproduction specialists is fundamental. Institutions like Ingenes offer:

  • Complete evaluation of ovarian reserve.
  • Egg or embryo freezing before oncological treatments.
  • Personalized IVF programs.
  • Genetic counseling, especially for women with BRCA mutations.
  • Emotional support throughout the entire process.

Each treatment must be adapted to the clinical and emotional situation of the patient, to offer not only the best chance of success but also a humane and respectful experience.

What Should You Ask Your Doctor?

If you have been diagnosed with ovarian cancer and are concerned about your fertility, some key questions to ask include:

  • How will my treatment affect fertility?
  • Is it safe to delay treatment to preserve eggs or embryos?
  • What fertility preservation options are most appropriate for me?
  • How long should I wait after treatment before trying to get pregnant?
  • How might my genetic mutation (if I have one) impact my future reproductive plans?

Conclusion

An ovarian cancer diagnosis changes life in many ways, but it does not mean the end of the dream of motherhood. Thanks to advances in reproductive medicine and fertility preservation programs, today there are more paths than ever for those facing this tough battle.

If you or someone close to you is facing an ovarian cancer diagnosis, you are not alone. At Ingenes, we bring all our experience, technology, and human commitment to help you preserve and build the family you desire.

Schedule a consultation and discover all the options that science and love for life have to offer you.

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