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As maternal age advances, the risk of developing numerical chromosomal abnormalities in babies increases.

In women over 40 years old, the likelihood of having a baby with some chromosomal anomaly is usually extremely high.

In the following graph, you can see the estimated risk of developing Down Syndrome according to maternal age.

What is

PGT-A?

Chromosomes carry our genetic material and are found in every cell of our body. In humans, each cell typically has 23 pairs of chromosomes, totaling 46, with 23 coming from the mother and 23 from the father. However, aneuploidy occurs when there is an extra or missing chromosome, and this imbalance is one of the leading causes of difficulty achieving pregnancy. It is associated with recurrent pregnancy loss, implantation failure, and certain syndromes.

PGT-A is a technique

Used during the In Vitro Fertilization (IVF) process that evaluates all 23 pairs of chromosomes in embryos. This allows us to determine which embryos are chromosomally normal with a 98% accuracy rate, which helps detect abnormalities associated with the number of chromosomes. By ruling out affected embryos, PGT-A increases the chances of giving birth to a healthy baby by allowing us to select the most viable embryos for transfer.
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By performing this test, the chances of your baby developing a condition such as Down syndrome, Patau syndrome, Turner syndrome, among others, are minimized.
The most important causes preventing parents from becoming pregnant are due to the genetics of the embryo. By analyzing the chromosomes of your embryos, the chances of giving birth to a healthy baby increase.

Could you be eligible for
a PGT-A test?

PGT-A is mainly recommended for individuals who fall under the following groups:
score-de-implantacion-embrionaria-para-tener-mas-exito-en-fertilizacion-in-vitro-doctor-especialista-en-fertilidad-junto-a-enfermera-mama-y-bebe-nacido-via-fecundacion-in-vitro-fiv
• Women who are 37 years old or older.

• Men who are 38 years old or older.

•Women with a history of pregnancy loss or recurrent miscarriages.

• Women with a history of implantation failure.

• Women who have experienced a decline in the quality of their eggs due to conditions such as endometriosis, polycystic ovary syndrome, or low egg production.
In addition, those who wish to choose the sex of their baby can also opt to undergo this test because by analyzing the sex chromosomes, PGT-A also allows for preimplantation sex determination, by selecting and transferring the embryos of the desired sex. 

What syndromes can be prevented with PGT-A?

PGT-A helps prevent the development of syndromes, a few of the most common ones include:
• Down syndrome (+21)
• Patau syndrome (+13)
• Edwards syndrome (+18)
• Klinefelter syndrome (XXY)
• Turner syndrome (OX)
• Triple X syndrome (XXX)
• Jacobs syndrome (XYY)
• Among other anomalies.
When undergoing assisted reproduction, your specialist will identify embryos with abnormalities and only select those that have the best chromosomal composition and do not show any genetic irregularities in terms of numbers. Transferring these selected embryos will increase the chances of a successful pregnancy.

PGT-A Test reduces risk of miscarriage.

How is the Preimplantation Genetic Test for Aneuploidy carried out?

At Ingenes, we perform the test the following way:
1.
This procedure is carried out at an In Vitro Fertilization (IVF) Laboratory by an Assisted Reproduction specialized biologist, who will carefully select the embryos with the best potential for analysis. 
2.
This technique begins with the biopsy collection without interfering with embryo development on the 3rd, 5th, or 6th day of development, to be analyzed with the help of advanced molecular biology techniques, using the best available technology on the market, Next Generation Sequencing (NGS).
3.
Genomic analysis is used to identify chromosomally normal embryos and determine their sex for selection and transfer during assisted reproduction treatments.
If you have any questions about PGT-A or are considering using this test to gain assurance about your future baby's well-being, your Assisted Reproduction expert will assess your case and guide you through this process. 

Leave your baby's health in expert hands

Our research team is dedicated to innovation and education in reproductive sciences, developing cutting-edge technology and tests such as PGT-A, in partnership with renowned researchers from Cinvestav-IPN.

Reach out to us and find the assurance you need with PGT-A

Get in touch with us to rule out genetic abnormalities in chromosomal numbers. Click on the following button to schedule your appointment and have our experts determine if you are a candidate for this test.
Schedule your appointment
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Dr. Felipe Camargo Cédula Profesional SEP: 4452501
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