Implementation failure

Implantation failure is the ultimate setback that can truncate the goal of achieving pregnancy. Find out why it happens, its symptoms and how we can help you.  

What is implantation failure?

Embryo implantation is a complex process that requires a healthy embryo and a receptive endometrium, as well as a close dialogue between the two. Implantation failure is diagnosed when it has not been possible to achieve a baby after at least three cycles of In Vitro Fertilization (IVF), or the transfer of more than ten good quality embryos.

Currently, there are highly effective solutions for implantation failure, among which the following stand out:
Embryo transfer at blastocyst stage (day 5 of embryo development)
Preimplantation genetic diagnosis
Assisted hatching or assisted hatching


The causes of implantation failure are multiple and may be involved with embryonic problems or problems in the uterus.

Embryonic problems include:
Chromosomal and genetic abnormalities
Difficulty of the embryo to emerge from the enveloping layer (zona pellucida)
Problems with the uterus include:
Anatomical alterations
Inadequate endometrial development
Benign tumours (myomas)
Scars, adhesions or synechiae
Infections or inflammation


Most women with pelvic adhesions have no symptoms, but some may have symptoms: 
Pelvic pain
Intestinal obstruction
Painful menstruation
Pain during sexual intercourse 
Increased incidence of ectopic pregnancies

Can I have a baby if I have implantation failure?

Knowing the precise causes of implantation failure is critical when it comes to selecting a treatment that will achieve a baby with the least amount of wear and tear.

When implantation failure is associated with immunological problems, these can easily be treated with medication; whereas, if it is due to problems with the uterus, treatment varies according to the cause and can range from hormone therapy to surgery in very specific cases.

However, when implantation failure is due to embryonic problems, the main treatments accompanying In Vitro fertilization include:
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